Weight management { Cholesterol &  Diabetes support }

Weight management { Cholesterol & Diabetes support }

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Useful properties :  clinically serves as an ideal remedy for the management and natural control of cholesterol, weight management, diabetes and related problems. 


Dosage : one capsule 1-2 times daily or as directed by the physician

A natural care for Diabetes, our vegan Diabetic care pills contain Trigonella foenum-graecum (Methi), Momordica charantia (Karela), Gymnema sylvestre (Meshashringi), Azadirachta indica (Neem), Syzygium cuminii (Jamun), Emblica officinalis (Amla), Tinospora cordifolia (Guduchi), Withania somnifera (Ashwagandha), Curcuma longa (Haldi), Cinnamomum zeylanica (Dalchini), Boerhaavia diffusa (Punarnava).

  • ●  Obesity eventually leads to type 2 diabetes, incorporation of fenugreek in the daily diet may assist with weight management. Scientists have reported several medicinal uses of fenugreek seeds such as remedies for diabetes and hypercholesterolemia.

  • ●  Bitter melon is traditionally known for its medicinal properties such as antidiabetic, and cholesterol lowering effects. It is also used as traditional anti-obesity medicine in Asian countries.

  • ●  Meshashringi has good prospects in the treatment of diabetes as it shows positive effects on blood sugar homeostasis, controls sugar cravings, and promotes regeneration of pancreas. The herbal extract is used in dietary supplements since it reduces body weight, blood cholesterol, and triglyceride levels.

  • ●  It is concluded from the present study that Neem may play a significant role in the management of type-2 diabetes mellitus, by improving the insulin signaling molecules and glucose utilization in the skeletal muscle. Neem flower extract has cholesterol-lowering effects by inhibiting intestinal cholesterol absorption, interfering micellar cholesterol formation, and attenuating cholesterol synthesis.

  • ●  The pup and seeds of jamun are used for traditional medicine against diabetes. Flavonoid-rich extract of S. cumini seed (300 mg/kg/day, 15 days) was described to reduce total cholesterol, LDL-cholesterol, and triacylglycerol as well as raise HDL-cholesterol levels.

  • ●  The high amount of vitamin C content in the fruit of Amalaki reduces the sugar level in blood. It strengthens the heart muscles and causes a significant decrease in total cholesterol, LDL cholesterol, VLDL cholesterol and triglycerides.

The stem of Guduchi is widely used in the therapy of diabetes by regulating the blood glucose in traditional folk medicine of India.

Study suggests that Ashwagandha root extract can be used for body weight management in adults under chronic stress.
Curcumin intake among patients with metabolic syndrome and related disorders was correlated with a significant reduction in BMI, weight, WC, and leptin, and a significant increase in adiponectin levels. Curcumin could favorably affect most of the leading aspects of diabetes, including insulin resistance, hyperglycemia, hyperlipidemia, and islet apoptosis and necrosis. Dalchini plant plays a vital role as a spice, but its essential oils and other constituents also have important activities like antidiabetic property. Cholesterol- and lipid-lowering effects of cinnamon were shown in many studies. The antiobesity effect of cinnamon was due to its insulin sensitivity, cardiovascular protection and immunomodulatory effects.

Punarnava can be taken in managing lipids and cholesterol in healthy limits. It is beneficial in treating obesity. Traditional uses of B. diffusa as anti-diabetic had been validated pharmacologically.

 

Ingredients

Each Hpmc vegan 750 mg capsule contains

Name of Ingredient

Latin Name

Qnty.

mg

Methi

Trigonella foenum-graecum

150

Karela

Momordica charantia

150

Meshasringi

Gymnema sylvestre

100

Neem

Azadirachta indica

100

Jamun

Syzygium cuminii

50

Amalaki

Emblica officinalis

50

Guduchi

Tinospora cordifolia

50

Ashwagandha

Withania somnifera

25

Haldi

Curcuma longa

25

Dalchini

Cinnamomum zeylanica

25

Punarnava

Boerhaavia  diffusa

25

 

 

 

Research

Methi :

● Sathyasurya Daniel Robert, 1 ,* Aziz Al-Safi Ismail, 2 and Wan Ishak Wan Rosli 3 : Trigonella Foenum-Graecum Seeds Lowers

1.

Postprandial Blood Glucose in Overweight and Obese Individuals.J Nutr Metab. 2014; 2014: 964873.
Published online 2014 Sep 3. doi: 10.1155/2014/964873.

● Shivangi Goyal, Nidhi Gupta, and Sreemoyee Chatterjee * : Investigating Therapeutic Potential of Trigonella foenum-graecum L. as Our Defense Mechanism against Several Human Diseases. J Toxicol. 2016; 2016: 1250387.
Published online 2016 Jan 18. doi: 10.1155/2016/1250387.

2. Karela :

  • ●  Baby Joseph* and D Jini : Antidiabetic effects of Momordica charantia (bitter melon) and its medicinal potency. Asian Pac J Trop Dis. 2013 Apr; 3(2): 93–102. doi: 10.1016/S2222-1808(13)60052-3.

  • ●  Bin Bao,# Yan-Guang Chen,# Lei Zhang, Yan Lin Na Xu, Xin Wang, Jian Liu, * and Wei Qu * : Momordica charantia (Bitter Melon) Reduces Obesity-Associated Macrophage and Mast Cell Infiltration as well as Inflammatory Cytokine Expression in Adipose Tissues. PLoS One. 2013; 8(12): e84075. Published online 2013 Dec 17.

    doi: 10.1371/journal.pone.0084075.

    3. Meshashringi :

● Pragya Tiwari, 1 B. N. Mishra, 2 and Neelam S. Sangwan 1 ,* : Phytochemical and Pharmacological Properties of Gymnema sylvestre: An Important Medicinal Plant. Biomed Res Int. 2014; 2014: 830285. Published online 2014 Jan 6. doi: 10.1155/2014/830285.

4. Neem :

  • ●  K. Satyanarayana,1 K. Sravanthi,2 I. Anand Shaker,1 and R. Ponnulakshmi3: Molecular approach to identify antidiabetic potential of Azadirachta indica. J Ayurveda Integr Med. 2015 Jul-Sep; 6(3): 165–174. doi: 10.4103/0975-9476.157950.

  • ●  Acharaporn Duangjai,1 Atcharaporn Ontawong,1,2 and Chutima Srimaroeng2,*: Siamese neem flower extract suppresses cholesterol absorption by interfering NPC1L1 and micellar property in vitro and in intestinal Caco-2 cells.Res Pharm Sci. 2019 Jun; 14(3): 190–200. doi: 10.4103/1735-5362.258485.

5. Jamun :

  • ●  Vinicyus Teles Chagas,1,2 Lucas Martins França,1,2 Sonia Malik,2 and Antonio Marcus de Andrade Paes1,2, : Syzygium cumini (L.) skeels: a prominent source of bioactive molecules against cardiometabolic diseases. Front Pharmacol. 2015; 6: 259.

    Published online 2015 Nov 3. doi: 10.3389/fphar.2015.00259.

  • ●  H. P. Gajera,corresponding author Shila N. Gevariya, Darshna G.

    Hirpara, S. V. Patel, and B. A. Golakiya : Antidiabetic and antioxidant functionality associated with phenolic constituents from fruit parts of indigenous black jamun (Syzygium cumini L.) landraces. J Food Sci Technol. 2017 Sep; 54(10): 3180–3191.

    Published online 2017 Aug 22. doi: 10.1007/s13197-017-2756-8.

    6. Amla :

  • ●  Dr. Pravin M Bhat, Dr. Hari Umale and Dr. Madhukar Lahankar : Amalaki: A review on functional and pharmacological properties. Journal of Pharmacognosy and Phytochemistry 2019; 8(3): 4378-4382.

  • ●  Prasan R. Bhandari, Mohammad Ameeruddin Kamdod : Emblica officinalis (Amla): A review of potential therapeutic applications. Int J Green Pharm 2012;6:257-69.

    7. Guduchi :

● Soham Saha and Shyamasree Ghosh : Tinospora cordifolia: One plant, many roles. Anc Sci Life. 2012 Apr-Jun; 31(4): 151–159.
doi: 10.4103/0257-7941.107344.

8. Ashwagandha :

● Dnyanraj Choudhary, MD,1 Sauvik Bhattacharyya, MPharm, PhD,2 and Kedar Joshi, MD3 : Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract A Double-Blind, Randomized, Placebo-Controlled Trial. J Evid Based Complementary Altern Med. 2017 Jan; 22(1): 96–106.

Published online 2016 Apr 6. doi: 10.1177/2156587216641830.

9. Haldi :

  • ●  Maryam Akbari, 1 Kamran B. Lankarani, 2 Reza Tabrizi, 1 Majid Ghayour-Mobarhan, 3 Payam Peymani, 2 Gordon Ferns, 4 Amir Ghaderi, 5 , 6 and Zatollah Asemi 7 , * : The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Pharmacol. 2019; 10: 649.

    Published online 2019 Jun 12. doi: 10.3389/fphar.2019.00649.

  • ●  Dong-wei Zhang, 1 ,* Min Fu, 2 Si-Hua Gao, 1 and Jun-Li Liu 2 ,* :

    Curcumin and Diabetes: A Systematic Review. Evid Based Complement Alternat Med. 2013; 2013: 636053.
    Published online 2013 Nov 24. doi: 10.1155/2013/636053.

    10.Dalchini :

  • ●  Pasupuleti Visweswara Rao 1 , 2 ,* and Siew Hua Gan 2 : Cinnamon: A Multifaceted Medicinal Plant. Evid Based Complement Alternat Med. 2014; 2014: 642942.
    Published online 2014 Apr 10. doi: 10.1155/2014/642942.

  • ●  Hamid Mollazadeh1 and Hossein Hosseinzadeh2,* : Cinnamon effects on metabolic syndrome: a review based on its mechanisms. Iran J Basic Med Sci. 2016 Dec; 19(12): 1258–1270.
    doi: 10.22038/ijbms.2016.7906.

    11.Punarnava :

  • ●  Debjit Bhowmik1, K.P. Sampath Kumar1*, Shweta Srivastava2, Shravan Paswan2, Amit Sankar2, Dutta Dutta3 : Traditional Indian Herbs Punarnava and Its Medicinal Importance. Vol. 1 No. 1 2012. Journal of Pharmacognosy and Phytochemistry.

  • ●  Mandeep Kaur and Rajesh Kumar Goel * : Anti-Convulsant Activity of Boerhaavia diffusa: Plausible Role of Calcium Channel Antagonism. Evid Based Complement Alternat Med. 2011; 2011: 310420. Published online 2011 Jan 9. doi: 10.1093/ecam/nep192

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